Asphalt paving will close Ferry Road between Portage Avenue and Bruce Avenue this weekend.
The city says the stretch of roadway will close to vehicle traffic on Saturday at 6 a.m. until Sunday evening.
While repairs are underway, both the northbound and southbound lanes will be closed.
Pedestrian access will be maintained on the east and west sidewalks.
Motorists should allow additional time to get to their destinations, and use alternate routes, the city said.