The city is closing Osborne Street South between Pembina Highway/Corydon Avenue and Mulvey Avenue East this weekend.
The closure is to accomodate girder and truss installation for the Southwest Rapid Transit Corridor overpass.
Traffic will be affected on Saturday beginning at 6 a.m. until Sunday at 10 p.m.
Winnipeg Transit will continue to operate their regular routes through the closure, but passengers may experience some delays.
Motorists can use alternate routes such as Jubilee Avenue and Pembina Highway.